What is a known complication of photodynamic therapy?

Photosensitivity is a well-documented complication of photodynamic therapy (PDT), which is a treatment that uses light-sensitive medications along with light to destroy cancer cells. After the administration of a photosensitizing agent, patients become more sensitive to light, particularly visible and ultraviolet light. This increased sensitivity can lead to adverse skin reactions when exposed to sunlight or bright indoor lighting, resulting in symptoms such as severe sunburn, redness, and blistering.

Understanding photosensitivity is crucial for patient management, as it necessitates specific precautions post-treatment, such as limiting sun exposure for a certain period and wearing protective clothing. This complication is directly related to the pharmacology of the photosensitizing agents used in PDT, highlighting the importance of educating patients about their care after undergoing such treatment.

The other options mentioned, while they can be associated with various medical conditions or treatments, are not typical complications arising specifically from photodynamic therapy.