What factor significantly increases the risk of rebleeding after endoscopic procedures?

One significant factor that increases the risk of rebleeding after endoscopic procedures is an ulcer size larger than 2 cm. Larger ulcers tend to be more vascular and can have deeper tissue involvement, which makes them more likely sources of bleeding. The increased area of the ulcer means that there is a higher likelihood of blood vessels being affected or damaged, thus elevating the chances of rebleeding even after treatment has been provided endoscopically.

In clinical practice, the size of the ulcer is an important consideration during endoscopic intervention, as larger ulcers may require more aggressive management, including additional procedures, medication adjustments, or follow-up surveillance to prevent rebleeding. Managing such larger ulcers effectively is crucial for improving patient outcomes, as they represent a more significant challenge in hemostasis.